POSSIBILITIES OF COMBINATION TREATMENT FOR PRESERVING THE SEXUAL FUNCTION IN PATIENTS AFTER RADICAL PROSTATECTOMY FOR LOCALIZED PROSTATE CANCER (2)
FINDINGS AND DISCUSSIONS
The analysis of the penile length measurement results proved that, 7 days after the surgery, the average shortening of the penis in the control group measured 0.73±0.08 cm, 30 days after the surgery it was 0.95±0.06 cm, and 3 months later it was 1.635±0.12 cm compared to the measurements made before the surgery (Fig. 1). Thus, 3 months after the surgery, the penile length shortening amounted to 12.45%.
In the second group of patients who took PDE-5 inhibitors, the average shortening of the penile length measured 0.75±0.08 cm 7 days post-surgery, 1.125±0.07 cm 30 days later and 1.175±0.08 cm 3 months later compared to the measurements made before the surgery (Fig. 2). According to the obtained data, the penile length shortening in the second group amounted to 10.26%, which is 2.19% less than in the control group.
The third group of patients, who combined the intake of PDE-5 inhibitors with the use of a vacuum extender, saw the average shortening of the penis measure 0.78±0.1 cm 7 days post-surgery (Fig. 3). After 30 days, a statistically significant increase in penis length by 0.175±0.08 cm was observed and after 3 months, the length increase measured 0.75±0.08 cm. Thus, despite the penis shortening by 5.7% by the 7th day, an increase in the penis length by 5.5% was observed by the 90th day compared to the initial data.
While assessing the test results in accordance with IIEF-5 Questionnaire, the following data were obtained: in the first group, the total score of the erectile dysfunction intensity before the surgery was equal to 16.5 points, by the seventh day after the surgery, it reduced by 6.45±1.3 points, which resulted in 9.7 points on average (Fig. 4). By the 30th and 90th days, an insignificant increase to 10.1 and 10.2 points, respectively, was registered.
In the second group, the total score of the erectile dysfunction intensity decreased by 6.45±1.3 points by the 7th day after the surgery, which resulted in 9.7 points (Fig. 5). By the 30th and 90th days, an increase in the total score was registered, namely 13.2 and 13.4 points respectively. When assessing the total score of erectile dysfunction in the third group, the obtained data did not exhibit any statistically significant difference from the results of the second group (Fig. 6).